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Evaluation ViewAttendees 2

Category: Health Psychology / Behavioral Medicine - Adult
Symposia

Symposium 63 - Examining the Various Stages of Domestic and Global Mental Health Interventions for HIV from Treatment Development Priorities to Treatment Response

Saturday, November 18, 2023
10:30 AM – 12:00 PM PST
Location: Tahuya (508), Level 5
CE: 1.5

Keywords: HIV / AIDS, Health Psychology, Global Mental Health
Level of Familiarity: Moderate
Recommended Readings: Safren, S. A., O'Cleirigh, C., Andersen, L. S., Magidson, J. F., Lee, J. S., Bainter, S. A., ... & Joska, J. A. (2021). Treating depression and improving adherence in HIV care with task‐shared cognitive behavioural therapy in Khayelitsha, South Africa: a randomized controlled trial. Journal of the International AIDS Society, 24(10), e25823.,   O'Cleirigh, C., Safren, S. A., & Mayer, K. H. (2012). The pervasive effects of childhood sexual abuse: Challenges for improving HIV prevention and treatment interventions. Journal of acquired immune deficiency syndromes (1999), 59(4), 331.,   Batchelder, A. W., Moskowitz, J. T., Jain, J., Cohn, M., Earle, M. A., & Carrico, A. W. (2020). A novel technology-enhanced internalized stigma and shame intervention for HIV-positive persons with substance use disorders. Cognitive and behavioral practice, 27(1), 55-69.,   ,  

 

HIV is a significant public health condition that affects more than 38 million people worldwide (WHO, 2021). There are effective treatments and prevention strategies that require adherence to daily medications—antiretroviral therapy (ART) or pre-exposure prophylaxis (PrEP)—for people with HIV (PWH) or at an increased risk for HIV acquisition. In these two groups, mental health conditions (e.g., depression, substance, post-traumatic stress disorder) are associated with decreased adherence to either ART or PrEP, increased likelihood of HIV transmission/acquisition, decreased engagement in care, worse HIV treatment outcomes, and poorer health-related quality of life (HRQoL). Behavioral HIV treatment and prevention interventions are efficacious and effective. However, the development of these interventions has multiple phases that each require nuanced study. Ultimately, these phases serve to produce cohesive intervention programs that can be implemented on a large scale to improve HIV treatment and reduce HIV incidence.

In this symposium, we present research conducted in Boston, MA, Miami, FL, Kwa-Zulu Natal (KZN), South Africa, and Cape Town, South Africa that spans various intervention development stages. These interventions address both HIV prevention and treatment for a variety of mental health conditions among diverse groups of participants. Presentations will examine: 1) intervention development priorities related to HRQoL among a sample of 14,000 people in KZN engaged in care; 2) feasibility and acceptability of a preliminary efficacy randomized controlled trial (RCT) among sexual minority men living with HIV and substance use disorders in Boston; 3) results of an RCT of cognitive behavioral therapy for trauma and self-care (CBT-TSC) to reduce condomless anal sex and posttraumatic symptoms among men who have sex with men who have histories of childhood sexual abuse in an effectiveness trial in Miami and Boston; 4) a qualitative exploration of feasibility and acceptability in an effectiveness trial of cognitive behavioral therapy for adherence and depression (CBT-AD) among PWH in Cape Town; and latent class analysis to examine classes of treatment response and predictors of class membership among PWH in Cape Town who received CBT-AD.

Learning Objectives:

At the end of the session, the learner will be able to:
  • Present an overview of various intervention development stages and examples of research conducted across the intervention development spectrum.
  • Present data and findings that: inform intervention development priorities using large datasets and suggest preliminary efficacy.
  • Present data and findings that: support effectiveness, explore feasibility and acceptability, and identify treatment responders.
  • Enhance understanding of mental health conditions associated with worse HIV-related outcomes and the effects of CBT-based interventions.
  • Be able to articulate considerations important to treatment development and identify differences between various stages of HIV interventions.

Presentations:

  • (SYM 63) Multimorbidity and Disease Control in Kwazulu-natal, South Africa: The Importance of Considering Health-related Quality of Life and Care Engagement in Behavioral Medicine Intervention Development

    Speaker: Amelia Stanton, Ph.D. (she/her/hers) – Boston University

    Co-author: Ryan Boyd, PhD (he/him/his) – The obelus Institute

    Co-author: Conall O'Cleirigh, Ph.D. (he/him/his) – Massachusetts General Hospital/Harvard Medical School

    Co-author: Stephen Olivier, PhD (he/him/his) – Africa Health Research Institute

    Co-author: Resign Gunda, PhD – Africa Health Research Institute

    Co-author: Olivier Koole, PhD (he/him/his) – columbia University

    Co-author: Dickman Gareta, MD (he/him/his) – Africa Health Research Institute

    Co-author: Tshwaraganang Modise, PhD – Africa Health Reserach Institute

    Co-author: Zahra Reynolds, MPH (she/her/hers) – Massachusetts General Hospital

    Co-author: Thandeka Khoza, PhD – Africa Health Research Institute

    Co-author: Kobus Herbst, PhD – Africa Health Research Institute

    Co-author: Thumbi Ndung'u, MD – Africa Health Research Institute

    Co-author: Willem Hanekom, MD – Africa Health Research Institue/University College London

    Co-author: Emily Wong, MD – Africa Health Research Institute

    Co-author: Deenan Pillay, PhD – University College London

    Co-author: Mark Siedner, MD – Massachusetts General Hospital/Harvard Medical School

  • (SYM 63) Feasibility and Acceptability of Project MATTER: A Compassion-based Psycho-behavioral Intervention for Sub-optimally Engaged Men Who Have Sex with Men Living with HIV and Substance Use Disorders

    Speaker: Abigail W. Batchelder, M.P.H., Ph.D. (she/her/hers) – Harvard Medical School/Massachusetts General Hospital

    Co-author: Abigail W. Batchelder, M.P.H., Ph.D. (she/her/hers) – Harvard Medical School/Massachusetts General Hospital

    Co-author: Hyo Shin, MPH (she/her/hers) – MGH

    Co-author: Hunter Baldwin, B.A. (they/them/theirs) – Fenway Health

    Co-author: Jacklyn D. Foley, Ph.D. – Massachusetts General Hospital

    Co-author: Matthew C. Sullivan, Ph.D. – Massachusetts General Hospital

    Co-author: Christopher Chiu, MA (he/him/his) – Massachusetts General Hospital

    Co-author: Kenneth Mayer, MD (he/him/his) – Fenway Health & Harvard Medical School

    Co-author: Conall O'Cleirigh, Ph.D. (he/him/his) – Massachusetts General Hospital/Harvard Medical School

  • (SYM 63) Cognitive Behavioral Therapy for Trauma and Self-care (CBT-TSC): Results of an RCT to Reduce Condomless Anal Sex and Posttraumatic Symptoms Among MSM Who Have Histories of Childhood Sexual Abuse

    Speaker: Conall O'Cleirigh, Ph.D. (he/him/his) – Massachusetts General Hospital/Harvard Medical School

    Co-author: Conall O'Cleirigh, Ph.D. (he/him/his) – Massachusetts General Hospital/Harvard Medical School

    Co-author: Gail Ironson, MD PhD (she/her/hers) – University of miami

    Co-author: Katie Biello, PhD – Brown University School of Public Health

    Co-author: Michael Boroughs, Ph.D., C.Psych – University of Windsor

    Co-author: Brett M. Goshe, Ph.D. – Massachusetts General Hospital

    Co-author: Samantha M. McKetchnie, LCSW – Massachusetts General Hospital

    Co-author: Jillian Shipherd, PhD – VA Central Office

    Co-author: Steven A. Safren, ABPP, Ph.D. (he/him/his) – University of Miami

  • (SYM 63) You Will Be Gaining Each and Every Time You Come Here”: Feasibility and Acceptability of a Task-shared Intervention for Adherence and Depression (CBT-AD) in People Living with HIV in South Africa

    Speaker: Lena Skovgaard Andersen, Ph.D. (she/her/hers) – University of Copenhagen

    Co-author: Lena Skovgaard Andersen, Ph.D. (she/her/hers) – University of Copenhagen

    Co-author: Maria Sofie Bach Danielsen, B.A. – University of Copenhagen

    Co-author: Jane Brandt Sørensen, PhD – University of Copenhagen

    Co-author: Amelia Stanton, Ph.D. (she/her/hers) – Boston University

    Co-author: Jessica F. Magidson, Ph.D. – University of Maryland, College Park

    Co-author: Jasper S. Lee, Ph.D. (he/him/his) – Massachusetts General Hospital (MGH)/Harvard Medical School

    Co-author: Ashraf Kagee, Ph.D. – Stellenbosch University

    Co-author: Conall O'Cleirigh, Ph.D. (he/him/his) – Massachusetts General Hospital/Harvard Medical School

    Co-author: Steven A. Safren, ABPP, Ph.D. (he/him/his) – University of Miami

    Co-author: John Joska, MBChB, FC, MMed, PhD – University of Cape Town

  • (SYM 63) Trajectories of Treatment Response in a Cognitive-behavioral Therapy Intervention for Depression and Adherence in PWH in South Africa

    Speaker: Jasper S. Lee, Ph.D. (he/him/his) – Massachusetts General Hospital (MGH)/Harvard Medical School

    Co-author: Jasper S. Lee, Ph.D. (he/him/his) – Massachusetts General Hospital (MGH)/Harvard Medical School

    Co-author: John Joska, MBChB, FC, MMed, PhD – University of Cape Town

    Co-author: Lena Skovgaard Andersen, Ph.D. (she/her/hers) – University of Copenhagen